Missing genes and sequencing read registration in single-cell RNA-seq experiments. Credit: Nature Methods (2023). DOI: 10.1038/s41592-023-02003-w In 2018, researchers in the Caltech laboratory of Yuki ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

As the body ages, organ function progressively declines and the risk for a wide range of diseases, including cardiovascular disease, cancer, and neurodegenerative diseases increases. Understanding how ...

A large-scale atlas of mouse brain cells has revealed that aging does not affect all brain cell types equally. Some cell populations show dramatic shifts in gene activity between youth and old age, ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

Summary: A team of investigators from Dana-Farber Cancer Institute, The Broad Institute of MIT and Harvard, Google, and Columbia University have created an artificial intelligence model that can ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

Livestock breeders could soon have more tools to improve the health and quality of their animals, thanks to a recent study that sheds new light on regulatory elements in the sheep genome.

Single-cell RNA sequencing of endometrial samples across the menstrual cycle identified key cell types and gene signatures ...